UN inspectors uncovered new evidence of "undeclared nuclear activities in Iran," the Wall Street Journal reported on Saturday.
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The report cites three diplomats as saying that samples taken by International Atomic Energy Agency staff members from two nuclear sites have indicated that traces of radioactive material exist.
The findings could suggest that the Islamic republic has launched new nuclear operations, the diplomats added.
As of Saturday morning, officials at the White House and State Department did not respond to requests for comment, the WSJ said.
While Tehran has claimed time and again that its nuclear project was meant for peaceful purposes, last year it has blocked IAEA inspectors from monitoring suspected sites.
Tensions between Iran and Israel, its arch-enemy, have risen to seething levels over the past few months.
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Top Israeli officials have triggered threats toward Tehran's nuclear ambitions, with Defense Minister Benny Gantz telling Alghad TV that "direct action" against Iran's nuclear facilities was on the table.
With the Biden administration seeking to rejoin the 2015 nuclear deal enacted during the tenure of Barack Obama as president, IDF Chief of Staff Lt. Gen. Aviv Kochavi urged the international community to maintain its pressure on Iran, which had developed advanced centrifuges that could allow it to build a nuclear warhead in months, if not weeks.
i24NEWS contributed to this report.