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Home Special Coverage Coronavirus Outbreak

Israeli doctor behind promising corona vaccine trial from US firm

The vaccine "was generally safe and well tolerated," Moderna says in a statement on Phase 1 testing.

by  i24NEWS and ILH Staff
Published on  05-19-2020 09:04
Last modified: 05-19-2020 09:32
Fears of top-level infection grow as 2 ministers, MKs quarantinedGetty Images

Israel may soon have to decide on steps on how to lift the lockdown | Illustration: Getty Images

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US biotech firm Moderna reported "positive interim" results on Monday in the first clinical tests of its vaccine against the coronavirus performed on a small number of volunteers.

In the eight trial subjects who received it, the vaccine, mRNA-1273, appeared to produce an immune response of the same magnitude as that observed in people convalescing from the virus, the company said.

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The clinical test was carried out by the National Institutes of Health, and the US government has invested a half-billion dollars in the development of Moderna's vaccine candidate.

Three groups of 15 patients received three different doses of the vaccine.

Dr. Tal Zaks

The complete results of the Phase 1 test, the first in the development of a vaccine and which in this case involved 45 participants, were not yet known.

The vaccine "was generally safe and well-tolerated," Moderna said in a statement.

"These interim phase 1 data, while early, demonstrate that vaccination with mRNA-1273 elicits an immune response of the magnitude caused by natural infection," Tal Zaks, Moderna's chief medical officer, said.

Phase 2 tests, with a larger number of subjects, should begin soon, according to Moderna. The Phase 3 trial, the last and most important to validate the efficacy of a vaccine, should begin in July.

Separate tests performed on mice showed that the vaccine prevented the virus from replicating in their lungs, according to the company.

Israel: 0 new COVID-19 cases for 1st time in months

Israel: 0 new coronavirus cases today for the 1st time in months. And just 3 cases in Tel Aviv & 1 case in Jerusalem going back 72 hours.

פורסם על ידי ‏‎Daily Dose with Jeff Smith‎‏ ב- יום שני, 18 במאי 2020

"The Moderna team continues to focus on moving as fast as safely possible to start our pivotal Phase 3 study in July," said Stephane Bancel, Moderna's CEO.

This article was originally published by i24NEWS.

Tags: CoronavirusCOVID-19Israel

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