Iran's Foreign Ministry has called a US agreement to set up a safe zone in northern Syria, a close ally of Iran, "provocative and worrisome," according to a report by the country's semi-official Fars news agency.
The United States and Turkey last week agreed to set up a joint operations center for a proposed zone along Syria's northeast border.
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The agency reported that "Foreign Ministry spokesman Abbas Mousavi ... said the recent announcements and agreements by American officials about creating a safe zone in northern Syria are provocative and worrisome."
Ankara and Washington agreed to establish a joint operation center in Turkey to coordinate and manage a planned safe zone in northeast Syria, a move that appeared to reduce the chance of imminent Turkish military action.
The two countries gave few details of the deal, which followed three days of talks between military delegations and months of stalemate over how far the safe zone should extend into Syria and who should command forces patrolling it.
The proposed zone aims to secure a strip of land stretching more than 400 km (250 miles) along Syria's northeastern border with Turkey, much of it controlled by the Kurdish YPG militia that fought with US support against Islamic State terrorists.
Ankara sees the YPG as terrorists who pose a security threat and has demanded that the United States sever its ties with the Kurdish militia.
The Syrian government has also blasted the agreement, which it said represented a "blatant attack" on Syria's sovereignty and territorial unity and a "dangerous escalation."
According to Damascus, the US-Turkish "aggression" represented "a dangerous escalation and a threat to peace and stability in the area."
